* Huntsman Cancer Institute, George S. & Dolores Eccles Auditorium, 6th Floor.

Transportation from Housing site provided from 5:00 - 8:00 pm every 15 minutes.

Mario Capecchi, Ph.D.
Howard Hughes Medical Institute, Department of Human Genetics University of Utah .

Transportation to Housing site provided from 8:30 - 10:00 pm every 15 minutes

Friday, May 17th, 2002

* Huntsman Cancer Institute, George S. & Dolores Eccles Auditorium, 6th Floor

7:00 - 8:00 am

Breakfast at Housing site

Transportation from Housing site provided from 7:00 - 8:30 am every 15 minutes

8:00 - 10:00 am

Session I:

Candidate Genes in Congenital Heart Disease

8:00 - 8:20 am

P.D. Grossfeld

The 11q Deletion Disorder: A Prospective Study of 120 Cases and Identification of a Candidate Gene for Heart Defects

8:20 - 8:40 am

Tatjana Piotrowski

The Zebrafish Van Gogh Mutant as a New Model to Study DiGeorge Syndrome

8:40 - 9:00 am

Hiroyuki Yamagishi

Tissue-specific Regulation of Tbx1 During Cardiovascular and Pharyngeal Arch Development

9:00 - 9:20 am

Anne M. Moon

An Fgf8 Mouse Mutant Phenocopies Human 22q11 Deletion Syndrome

9:20 - 9:40 am

Erik N. Meyers

Fgf8 Is Required for Pharyngeal Arch Development and Cardiovascular Patterning in the Mouse

9:40 - 10:00 am

Francesca Vitelli

Tbx1 and Fgf8 Interact Genetically During Aortic Arch Development

10:20 - 12:20 pm

Session II:

Transcriptional Regulation of Heart Development

10:20 - 10:40 am

J.R. Korenberg

Gene Expression and Mouse Models From the Down Syndrome CHD Consensus Region

10:40 - 11:00 am

Youngsook Lee

Molecular Characterization of JUMONJI, a Critical Factor for Cardiac Development

11:00 - 11:20 am

Anthony B. Firulli

PKC, PKA, and PP2A Modulate Dimerization of HAND class bHLH Factors: A Mechanism for Tissue Specific Gene Expression

11:20 - 11:40 am

Carl O. Brown III

A Novel Enhancer of Nkx2-5 is Cooperatively Activated by GATA and Smad Transcription Factors

11:40 - 12:00 am

Mabelle Ashe

LEK1 is a Potential Universal Regulator of Pocket Protein Activity

12:00 - 12:20 pm

Henry M. Sucov

Epicardial Induction of Fetal Cardiomyocyte Proliferation via a Retinoic Acid-Inducible Trophic Factor

1:40 - 3:40 pm

Session III:

Differentiation Signaling Pathways

1:40 - 2:00 pm

Deborah Yelon

Retinoic Acid Signaling Restricts Myocardial Differentiation Within the Heart Field

2:00 - 2:20 pm

Anthony D. Person

A Role for Wnt Signaling in Atrioventricular Valve Department

2:20 - 2:40 pm

Glenn I. Fishman

Neuregulin-1 Promotes Murine Cardiac Conduction System Differentiation

2:40 - 3:00 pm

Georges Nemer

Cooperative Interaction Between GATA-5 and NF-Atc Regulates Endothelial-Endocardial Differentiation

3:00 - 3:20 pm

Michael T. Chin

A Mouse Model of Ventricular Septal Defect

3:20 - 3:40 pm

Manuel Utset

Congenital Heart Defects in Hey2 Mutant Mice

Poster Session

* Primary Children's Medical Center 3rd Floor Multipurpose Room Transportation from Huntsman Cancer Institute provided from 3:45 - 4:45 pm every 15 minutes Transportation from Primary Children's Medical Center to Housing site provided from 4:45 - 6:45 pm every 15 minutes

Saturday, May 18th, 2002

* Huntsman Cancer Institute, George S. & Dolores Eccles Auditorium, 6th Floor

7:00 - 8:00 am

Breakfast at Housing Site

Transportation from Housing site provided from 7:00 - 8:30 am every 15 minutes

8:00 - 9:40 am

Session IV:

Novel Roles of Structural Proteins

8:00 - 8:20 am

Isae Shiraishi

Immunolocalization of RHO During Myofibrillogenesis of Whole-Mounted Mouse Embyronic Heart Tubes

8:20 - 8:40 am

Joseph W. Sanger

A New Dynamic Property of Cardiac Muscle Myosin II

8:40 - 9:00 am

K.A. Clark

Using Drosophila as a Model System to Define the Molecular Mechanism of Muscle LIM Protein (MLP) Family Members

9:00 - 9:20 am

Thomas Bartman

A Mutation in a Novel Actin Disrupts Endocardial Cushion Formation in Zebrafish

9:20 - 9:40 am

Steven A. Vokes

Endoderm Is Required for Vascular Endothelial Tube Formation, But Not for Angioblast Specification

9:40 - 10:00 am

S. Karnik

Elastin Regulates Vascular Smooth Muscle Cell Actin Polymerization and Migration Through G Protein Signaling

8:00 - 9:40 am

Session V:

Left-Right Signaling and Morphogenesis

10:20 - 10:40 am

K.L. Kramer

Syndecan 2 is Asymmetrically Regulated by PKC During Early Xenopus Left-Right Development

10:40 - 11:00 am

Shusheng Wang

A Role for the Polycomb Group Gene TDP in the Regulation of Establishment of Left-right Aysmmetry in the Chick

11:00 - 11:20 am

J. Lohr

Effect of TGFbeta Proteins on Cardiac Asymmetry

11: 20 - 11:40 am

James F. Martin

Pitx2c Patterns Anterior Myocardium and Aortic Arch Vessels and is Required for Mesenchymal Invasion of Atrioventricular Cushions

11:40 - 12:00 am

Wilmer Roberts

Rho Kinases are Essential for Early Laterality Specification and for Proper Embryonic Morphogenesis

12:00 - 12:30 pm

Lunch

Seating available at the Point Restaurant and conference rooms on floors 3 & 4

1:20 - 3:20 pm

Session VI:

Morphogenesis and Neural Crest

1:20 - 1:40 pm

Talât Mesud Yelbuz

Optical Coherence Tomography (OCT)- A New Method to Study Cardiac Morphology and Development in Chick Embryos

1:40 - 2:00 pm

Heather Barlett

Truncated Nkx 2.5 Prolongs the Interval Between Atrial and Ventricular Contractions in Xenopus Embryos

2:00 - 2:20 pm

S. Fisher

Role of the Death Receptor Pathway in Heart Development

2:20 - 2:40 pm

P.R. Brauer

The Role of Matrix Metalloproteinase Inhibitors in Cardiac Neural Crest Cell Migration

2:40 - 3:00 pm

Marit J. Boot

Early- and Late-Migrating Cardiac Neural Crest Cells Have Different Migration and Differentiation Capacities

3:00 - 3:20 pm

X. Xu

Connexin43 Modulation in Integrin Signaling Plays an Essential Role in Cardiac Neural Crest Cell Migration

3:30 - 6:00

Poster Session

* Primary Children's Medical Center 3rd Floor Multipurpose Room

Transportation from Huntsman Cancer Institute provided from 3:15 - 4:15 pm every 15 minutes

Transportation from Primary Children's Medical Center to Housing site provided from 4:15 - 6:15 pm every 15 minutes

7:00 - 11:30

Awards Banquet at Log Haven

Transportation to Log Haven leaves Housing at 6:15 pm

Transportation to Housing leaves Log Haven at 11:30 pm

12:00 Noon

Checkout. See you next year!