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Huntsman Cancer Institute investigator Katharine Ullman, PhD, is an assistant
professor in the Department of Oncological Sciences at the University of Utah School of Medicine and
an adjunct assistant professor in the Department of Biochemistry at the University of Utah.
Ullman and her research team focus on nuclear pore function. Nuclear pores provide a gateway
between the nucleus and cytoplasm through which RNAs and proteins travel. It is important to have a
connection that allows communication between the nucleus and cytoplasm, but at the same time prevents
unrestricted entrance into the nucleus. This allows the nucleus to harbor a specialized environment,
optimized to protect and regulate the cell's DNA. When this gateway operates improperly and allows
inappropriate molecules to pass into the nucleus, genes can be mis-regulated, contributing to the
development of cancer. Ullman's laboratory investigates how proteins in nuclear pores help to guide
specific cargo en route through the pore.
Ullman earned a PhD from Stanford University in 1992 before going to the University of California
at San Diego for her postdoctoral studies, which were funded in part by the American Cancer Society.
She joined Huntsman Cancer Institute in 1998 and is a recipient of a Burroughs Wellcome Career Award
in the Biomedical Sciences.
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