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The Sarcoma Array Research Consortium (SARC) is a state-of-the art molecular
biology lab at Huntsman Cancer Institute. The main focus of the lab is
investigating the manner in which cancer genes are expressed in sarcomas.
R. Lor Randall, M.D., F.A.C.S., Director, Sarcoma Service and Chief, SARC
lab works closely with David Joyner, PhD, and their research team. Other
scientists and investigators at HCI also collaborate on studies being carried
out in the lab.
One of the central missions of SARC is the use of gene (cDNA) microarray
technology to aid in the development of a molecular taxonomy for sarcomas.
In a joint effort with universities around the country, the SARC lab is able
to process and analyze donated tissue samples and report back to collaborators.
The SARC lab also has mechanistic experiments looking at genes involved in
regulating programmed cell death or apoptosis in sarcomas. Particular interests
to our investigators include developing new treatments for synovial sarcoma and
Ewing's Sarcoma, deadly cancers that afflict children and young adults.
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