Nuclear Pore Complexes - Ullman Lab

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•	Nup153
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•	Pore and Envelope Disassembly
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		The nuclear pore complex is a huge macromolecular structure (120 MDa in vertebrates). Although individual components of the nuclear pore have been identified at a molecular level, a major challenge in the field is to understand how these components cooperate to direct regulated, bi-directional movement of cargo. Each pore is estimated to guide the transport of over 100 molecules per minute. Yet, despite the “high through-put” nature of this process, transport occurs with specificity.
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Last Modified: Tuesday, September 6, 2005

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