Description

The research of the Cell Response and Regulation (CRR) Program spans the spectrum of basic to translational research. Members study fundamental cellular mechanisms that are deregulated in cancer cells, and this research leads to identification and validation of potential targets for therapeutic intervention.

Research programs of CRR members cluster within the following interest groups:

• mechanisms of cell growth and death
• intracellular signaling
• cell behavior within specialized microenvironments

Several members use animal models to characterize cell and tumor behavior in organisms. The diverse expertise in techniques and model systems offers great opportunity for synergistic projects and stimulating scientific exchange.

The Cell Response and Regulation Program currently draws members from many academic units on campus. The program provides a forum for interdepartmental communication among individuals who share a common interest in understanding the cellular basis of cancer.

The Cell Response Program currently receives approximately $17,073,356 per year of direct, and $23,199,726 of total research support from the NCI, other NIH institutes, the American Cancer Society and other funding agencies. Cancer focused articles published in 2007 total 73 including 8 inter-programmatic and 8 intra-programmatic publications.

Douglas, Grossman, MD, PhD
Co-leader

Katharine Ullman, PhD
Co-leader

Members