(May 1, 2000 to April 30, 2001)

Amifostine and UVB-induced Apoptosis in Keratinocytes

Principal Investigator: Douglas Grossman, MD, PhD

Department: Dermatology

Casein Kinase Ie and Wnt Signaling in Intestinal Neoplasia

Principal Investigator: David Virshup, PhD

Department: Oncological Sciences

Topoisomerase I Sensitizers, a New Class of
Therapeutics: in vivo Assessment

Principal Investigator: Louis R. Barrows, PhD

Department: Pharmacology and Toxicology

Developing a Mouse Model for Infant Leukemia

Principal Investigator: William B. Slayton, MD

Department: Pediatrics

Investigation of the Role of TEL/AML-LB
in Transcription and Leukemia using a B-cell Model System

Principal Investigator: Martha Glenn, MD

Department: Internal Medicine

Mutational Studies of the Drosophila p53 Tumor Suppressor Gene

Principal Investigator: Yikang Rong, PhD

Department: Biology

Structural Basis for the Mechanism of Ubiquitinylation by the SCF Complex

Principal Investigator: Christopher Hill, PhD

Department: Biochemistry