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Former
Lab Members
MILES PUFALL Miles was a member of Dr. Graves’
Lab from 1999 to 2005, receiving his PhD in December of 2004. His work
focused on understanding mechanisms of DNA binding regulation, using Ets-1
as a model. Employing a combination of biochemical, biophysical, and structural
techniques, including NMR, Miles was able to show that multiple phosphates
worked together additively to fine tune DNA binding affinity, rather than
simply turn DNA binding on or off. This work earned him the James W. Prahl
award for outstanding contributions by a graduate student in the biomedical
sciences. He is currently conducting his post-doctoral research in the
lab of Keith Yamamoto at the University of California at San Francisco.
Miles received his BA in Chemistry from Oberlin College, and his MS in
Toxicology from American University.
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